Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

Adoptive transfer of chimeric antigen receptor-transduced T cells is a promising strategy for cancer immunotherapy.The CD38 molecule, Face Masks with its high expression on multiple myeloma cells, appears a suitable target for antibody therapy.Prompted by this, we used three different CD38 antibody sequences to generate second-generation retroviral

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The relationship between relative age effects and sex, age categories and playing positions in Brazilian National Handball Teams

Abstract Aims: This study investigated the existence ORG GF THICK ROLLED OATS of Relative Age Effect (RAE) in the selection process of male and female athletes in the Brazilian national handball teams according to age categories (U-18, U-21, and senior) and playing position (wings, backs, pivots, and goalkeepers).Methods: In order to determine RAE,

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WWI Armenian Refugees Census Data as a Source for Ottoman Armenian Population Numbers on the Eve of the Armenian Genocide

This paper aims to present and analyze data provided by censuses of the Ottoman Armenians from Van, Erzeroum and Bitlis provinces, who, fleeing the threat of massacre during WWI, found refuge in the territory of the Russian Empire, particularly in the Russian Transcaucasia.By comparing data on the Armenian refugees with information provided by othe

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